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Since most glucose-dependent insulinotropic polypeptide (GIP) receptor: glucagon-like peptide- 1 receptor (GLP- 1) receptor: glucagon receptor triagonists compete in efficacy with bariatric surgery, the success of these agents in preclinical models and clinical trials suggests a bright future for multi-agonists in the treatment of metabolic diseases

As previously mentioned, much work is still needed to improve our understanding of the relationships among multiple signaling pathways

PMC 9385790

For a given established pathway, we tested its first-degree neighboring members for significant association with the pathway

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