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Similarly, 5-methylcytosine (5 mC) is directly oxidized to 5-hydroxymethylcytosine (5-hmC), rendering it unrecognizable by DNA methyltransferases and leading to changes in the overall methylation pattern

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In our study, we found that when these filters end up in waterbodies, they are increasingly colonized by potentially pathogenic bugs and bacteria displaying antibiotic resistance, as these are particularly well adapted to the adverse conditions on the filters. The research group found that cigarette waste not only pollutes the environment but also poses significant public health risks

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A recent review of therapeutic drug monitoring data demonstrated a reduction in concentration/dose of amitriptyline, escitalopram and mirtazapine in smokers, even when age and sex variables were accounted for [25]
