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The dramatic spikes in youth e-cigarette use back in 2017 and 2018, primarily driven by JUUL, showed us how quickly e-cigarette sales and use patterns can change, said Deirdre Lawrence Kittner, PhD, MPH, director of CDCs Office on Smoking and Health

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it is also produced in the Eastern United States (mostly in Florida, Kentucky, Tennessee, and Virginia) and in the Mediterranean countries of Italy, Greece, Spain (in the Canary Islands), and Turkey, and to a lesser degree in Indonesia and the Philippines of Southeast Asia