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These microbial shifts, along with changes in 71 KEGG pathways, highlighted the potential for EC use to contribute to periodontal disease through its impact on the oral microbiome [66]

Smokers who exercise have better peripheral blood flow [3], but chronic increase in ET-1 can limit both exercise-induced vasodilation and blood flow in muscles [19]

doi: 10.1001/jamanetworkopen.2020.20816 51

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Return of cartoon to market e-cigarette-related products

Stores should not sell cigarettes or, at the very least, not to anyone under 30