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Centers Center for Research on Tobacco and Health On This Page In This Section Center for Research on Tobacco and Health Welcome to Penn State Center for Research on Tobacco and Health Penn State Center for Research on Tobacco and Healths mission is to be a national leader of scientific discovery that will translate into effective interventions and policies to reduce tobacco-caused harm in our communities

In brief, the measurements were performed using a Shimadzu Prominence HPLC (Shimadzu, Reinach, Switzerland) coupled to a SCIEX 4000 QTrap mass spectrometer (AB Sciex, Darmstadt, Germany) and a PAL autosampler (CTC Analytics, Zwingen, Switzerland)

Data analyses were conducted within a Bayesian framework, which supports inferences beyond binary reject-not reject decisions about null hypotheses, provides a continuous measure of evidence in support of those inferences, and accounts for uncertainty in those inferences (eg, due to an inflated false discovery rate often attributable to multiple comparisons) up front via the specification of default prior distributions on parameters of interest

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