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Allergic reactions: Although uncommon, allergies can be serious

Slow Gastric Emptying By slowing the rate at which the stomach empties after meals, semaglutide increases feelings of fullness for longer periods, helping control portion sizes and reduce snacking

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Further, GLP-1RAs block the adhesion of monocytes to endothelium induced by oxidized LDL via extracellular signal-regulated kinase (ERK) 5-Kruppel-like factor (KLF)2 signaling pathway to prevent endothelial permeability [107, 108]