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24,37 GLP-1 RAs have been associated with improved renal outcomes, including enhanced natriuresis and reduced albuminuria, which are beneficial in diabetic kidney disease

Patient and public involvement No patient representatives or members of the public were directly involved in the planning, design, conduct, or reporting of this study, and no primary data were collected

In particular, in both studies, liraglutide 1.8 mg/day induced a significant increase in SHBG and a decrease in free testosterone

doi: 10.1016/S0140-6736(18)32260-8 112 FrasJPDaviesMJRosenstockJPrez ManghiFCFernndez LandLBergmanBKet al

The retatrutide dosing protocol follows a similar escalation pattern to tirzepatide, starting low and increasing over several months

The DIAZOB primary care diabetes study
