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We found that GLP-1 RA use was associated with a modestly higher incidence of psoriasis and lower incidences of pemphigus and bullous pemphigoid compared with DPP-4i use, while no increased risk was observed for most other autoimmune or inflammatory skin diseases

This creates a vicious cycle: stress raises cortisol, cortisol drives weight gain and appetite, and impaired GLP-1 signaling perpetuates the problem

[DOI] [PMC free article] [PubMed] [Google Scholar] 346.Llewellyn-Smith I.J., Reimann F., Gribble F.M., Trapp S

p38 MAPK: p38 mitogen-activated protein kinase

Liu Y, Song X, Zhang Y, Zhou L, Ni R

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