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The effectiveness of hydroxychloroquine in patients with type 2 diabetes mellitus who are refractory to sulfonylureasa randomized trial

doi: 10.1016/S0140-6736(15)00803-X 36 BendottiGMontefuscoLLunatiMEUsuelliVPastoreILazzaroniEet al

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Circulation 2023;149:204216

This interpretation is consistent with clinical observations that oral glutathione supplementation has limited bioavailability, favoring approaches that maintain precursor sufficiency instead of direct replacement [117,118,119]