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The role of glucagon in glucose intolerance and effects of GLP-1 based drugs on plasma glucagon
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Current regulatory guidance maintains that GLP-1 RAs and GIP-GLP1RA are contraindicated in people with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2)

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It is commonly prescribed as part of a structured medical weight loss program

Cardiovascular effects in experimental models Effects on atherosclerosis