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GLP-1 exerts additional metabolic benefits by suppressing glucagon secretion, delaying gastric emptying, and reducing appetite
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Clostridium butyricum increases butyrate production in the colon, which draws water into the intestinal lumen through osmotic effects
Demand for the drugs, which were initially designed to treat type 2 diabetes, increased since the Food and Drug Administration approved Wegovy for weight loss in 2021
Both lixisenatide (79) and liraglutide (80) have also been reported to increase chylomicron triacylglycerol clearance
