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During GLP-1 therapy, patients learn what balanced hunger feels like so that when medication support fades, those signals are familiar rather than frightening

Raed Alhusayen, a Toronto dermatologist who was not involved in the study, commented on the potential mechanism of action: Semaglutide medications like Ozempic and Wegovy may help manage HS primarily by promoting weight loss

Similar content being viewed by others Introduction Glucagon-like peptide-1 (GLP-1), an incretin hormone secreted by L-cells in the distal ileum and colon 1 , has various effects, including glucose-dependent enhancement of insulin secretion 2 , inhibition of glucagon secretion 3 , appetite suppression 4 , and suppression of gastric emptying 5

References 1 EustachiBPiniPM

As semaglutide has a half-life of 7 days, 50% of semaglutide remains in the body after 7 days, and the concentration drops to 25% of the initial concentration after 14 days

It should be used with a reduced-calorie diet and increased physical activity, in line with the UK approval announced by the MHRA