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Regarding renal function, no dose adjustment is required for patients with renal impairment, including those with end-stage renal disease

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For some patients with mild disease, those steps may meaningfully reduce symptoms

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Hormonal fluctuations throughout the menstrual cycle can also create more week-to-week variability in women, making the trend line harder to read but not fundamentally different in terms of total outcomes at six and twelve months

Antibody cross-reactivity with native GIP and GLP-1 was seen in 40% and 16.5%, respectively