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Description
Risk of thyroid cancer in GLP-1 receptor agonist users

Two trials, the AHEAD Study (lecanemab) and TRAILBLAZER-Alz-3 (donanemab), are now in the process of evaluating the effect of these therapies on the prevention of disease progression in people at high risk of AD, as measured by time to clinical progression (AHEAD Study, 2024

A 2024 study led by Wang, Volkow, and colleagues examined two cohorts totaling over 682,000 individuals with either obesity or type 2 diabetes and found the risk of new alcohol use disorder diagnoses was about 50% lower among those taking semaglutide compared to other anti-obesity or diabetes medications (Wang et al., 2024a)

Consider EOD (every other day) dosing before increasing total dose

There is no current evidence that retatrutide reduces cardiovascular events

Targeting metabolic diseases: the role of nutraceuticals in modulating oxidative stress and inflammation
