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Some cases have resulted in hospitalization

In a Danish trial, adults near retirement did one year of heavy resistance training and, four years later, still held their leg strength while the non-trainers had measurably declined (Bloch-Ibenfeldt et al., 2024)

This suggests that these are being increasingly used off-label for weight loss and other non-diabetes indications

The mice treated with GLP-1 medication were more mobile and more physically capable than the untreated obese control group

Skipping a weekly semaglutide injection can temporarily disrupt appetite suppression and weight loss momentum, but one missed dose is not a treatment failure