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With this notion, the study of these molecular transducers has been approached by some authors in recent years from a top-down point of view, whereby sub-type specific, allosteric positive or negative modulators (PAM, NAMs), as well as direct agonists, are utilized as tools for pathway dissection and analysis ( The expression of different GPCRs to restricted anatomical regions, such as the enteroendocrine cell system, is a finely tuned system that evolved in metazoan

INTRODUCTION Glucagon-like peptide-1 (GLP-1) is a peptide that is primarily produced by the endocrine cells in the gut in response to nutrient intake[1]

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Clinicians should talk to their patients about the foods and beverages they consume and advocate for dietary changes that may promote brain health starting early in life, decades before people start exhibiting cognitive decline

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Exendin-4 alleviates retinal vascular leakage by protecting the blood-retinal barrier and reducing retinal vascular permeability in diabetic Goto-kakizaki rats