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14.2 Use in Pregnant Women 14.2.1 Potential Risks to Fetus Limited data exist regarding fetal safety

Some patients report localized itch at the injection site, especially in cases where people injected the same area repeatedly, Rodney points out
Even small amounts of moisture absorption can trigger hydrolysis reactions that break peptide bonds, leading to fragmentation and loss of biological activity
Roland Staud, M.D., professor of medicine at the University of Florida, and colleagues have demonstrated that FM patients have (increased sensitivity to pain (hyperalgesia), yet modulate pain input as effectively as healthy controls, suggesting amplified pain in the central nervous system
Such projections demonstrate the critical need to reimagine care and therapy within the field

bioRxiv 2020 Sep 30 .Article 43
