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Prioritize Hydration: Slowed digestion means your body needs more water to keep stool soft

Several physiological mechanisms explain why rapid weight loss promotes gallstone formation: Altered bile composition : During significant caloric restriction and rapid fat mobilisation, the liver secretes increased amounts of cholesterol into bile whilst bile salt secretion remains relatively constant, creating cholesterol-supersaturated bile Reduced gallbladder motility : Decreased food intake, particularly reduced dietary fat, means less frequent gallbladder contraction and emptying, allowing bile to stagnate and cholesterol crystals to form Increased cholesterol mobilisation : As adipose tissue is broken down, cholesterol is released into the circulation and subsequently excreted via bile Studies of patients undergoing bariatric surgeryanother intervention causing rapid weight losshave demonstrated gallstone formation rates of 3050% within the first year post-operatively when prophylactic measures are not employed, though many of these stones remain asymptomatic

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With the right treatment and support, many individuals lead active, normal lives

Int J Mol Sci 23(16):9127 Singh U, Devaraj S, Jialal I, Siegel D (2008) Comparison effect of atorvastatin (10 versus 80 mg) on biomarkers of inflammation and oxidative stress in subjects with metabolic syndrome