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GLP-1 (glucagon-like peptide-1) receptor agonists are medications that mimic hormones your body produces naturally after eating

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[Google Scholar] [6].Abu-Hamdah R, Rabiee A, Meneilly GS, Shannon RP, Andersen DK, Elahi D, Clinical review: The extrapancreatic effects of glucagon-like peptide-1 and related peptides, J Clin Endocrinol Metab 94(6) (2009) 184352

In previous GLP-1- or exendin-P5-bound active structures 3,4 , the ECD shows a fully extended open conformation, whereas in the peptide 5-bound active-like structure 12 , the ECD is less extended since it makes fewer interactions with the truncated peptide 5

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