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Several pharmaceutical companies are racing to introduce their own weight loss drugs to the market and disrupt the current duopoly held by Novo Nordisk and Eli Lilly

Should GLP-1RAs be paused preoperatively

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A new FDA-approved weight loss pill is entering the market this month

They postulate that the enhanced export of bile acids out of hepatocytes and a reduction of bile acid synthesis via inhibition of CYP7A1, which converts cholesterol to bile acids, were mediated by increased GLP-1 in DPP4-KO rats (48)

2024) as a significant therapeutic option for individuals with T2DM, especially those with preexisting atherosclerotic cardiovascular diseases or at a heightened cardiovascular risk