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PubMed 41.Pratley R, Amod A, Hoff ST, et al

It is also worth considering that fatigue attributed to GLP-1 therapy may actually reflect underlying conditions such as hypothyroidism, anemia, sleep apnea, or depression, which should be evaluated if tiredness persists

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Age-related changes in body composition and their sequelae Progressive change in body composition occurs with ageing, characterised by four phenotypes in older adults, that can increase the likelihood of mortality through comorbid disease [11]: sarcopenia, healthy weight, obesity and sarcopenic obesity [12] (Fig

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Studies show that melatonin activates receptors to boost P-glycoprotein transporter activity, crucial for BBB function, particularly in methamphetamine-induced toxicity in rat brain endothelial cells [186]