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While DHEA is a natural substance, I would encourage serious caution (definitely talk to a doctor!) with using DHEA if you are young, pregnant, breastfeeding, or being treated for hormone-related cancer

Melena is concerning because it may point to bleeding in the stomach or upper small intestine

or dialysis

Oral absorption of small molecules without enhancers mostly occurs in the intestine, and this has been assumed to be the case for peptide-based drugs with enhancers

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With a diet rich in proteins, vitamins and minerals essential for skin health, maintaining proper nutrition can help to tighten skin, keeping it strong and supple