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The follow-up durations ranged from 12 to 104 weeks

And they found that the mice lost weight, increased sympathetic activity, increased BAT temperature in the scapular region, and increased thermogenesis

According to etiology, it is classified into five groups: group 1pulmonary arterial hypertension due to vascular remodeling of the pulmonary arteries, group 2pulmonary hypertension associated with left-sided heart failure, group 3pulmonary hypertension associated with lung disease, group 4pulmonary hypertension associated with pulmonary artery obstructions, and group 5pulmonary hypertension with unclear and/or multifactorial mechanisms

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