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Description
On March 20, 2026, Chinas patent on semaglutide (the active ingredient in Ozempic and Wegovy) expiresyears ahead of patent expirations in the U.
Whether the positive impact of GLP-1RAs on hepatic histology is indirect, i.e., through their action on extrahepatic tissues, or whether their action is direct, i.e., through activating GLP-1R on the hepatocytes, is still a controversial issue

Eli Lilly have a new, once-monthly GLP1/GIP agonist (Brenipatide) and they're running some fascinating trials with it Smoking cessation, bipolar disorder, schizophrenia, opioid use disorder, depression, alcohol use disorder, and asthma
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Retatrutide UK from Astra Labs best triple GLP-1/GIP/Glucagon agonist research compound

Large study hints GLP-1 medicines may reduce substance-use disorders
