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Measurements (optional but valuable): Waist circumference and hip circumference can reveal body composition changes before the scale moves

A baseline DEXA or InBody scan plus a follow-up at month three makes this measurable instead of theoretical

The newer drugs go further

Leptin signaling in the medial nucleus tractus solitarius reduces food seeking and willingness to work for food

Under the CV indication, patients with established cardiovascular disease and BMI 27+ qualify, and the 6-month lifestyle program is waived on most plans