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While polygenetic risk scores estimate a persons inherited genetic susceptibility based on multiple common genetic variants, a clinical diagnosis reflects observable symptoms and behaviors, which may be influenced by both genetic and environmental influences

This pattern is compatible with the idea that there is an optimal level of DA and NA in the prefrontal cortex

(2004) reported that two SNPs (rs2056202 and rs2292813) in the mitochondrial aspartate/glutamate carrier gene SLC25A12 are associated with autism [26]

Lesions are very similar to those induced by AKAV and include arthrogryposis, brachygnathia inferior, torticollis, kyphosis, lordosis, scoliosis, cerebellar hypoplasia, hydranencephaly, porencephaly, hydrocephalus, and micromyelia (Fig

Atherosclerosis refers to lipid deposition (mainly cholesterol and cholesteryl ester) in the intima and subintima of arteries

2008, PMC2431115)