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Neuroprotectant or antioxidant compounds may exert positive effects when associated with antiepileptic drugs (AEDs)

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This suggests that energetically, pheomelanin is more likely to be involved in a radical-producing reaction than eumelanin

Annu Rev Pharmacol Toxicol 45:5188 Kato R, Yamazoe Y (1994) Metabolic activation of N-hydroxylated metabolites of carcinogenic and mutagenic arylamines and arylamides by esterification

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