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1), S59S66

Nothing is standardised to the point of ignoring individual variation

Notch signals are involved in multiple cellular processes, including cell survival, differentiation, apoptosis, and regeneration (Siebel and Lendahl 2017)

We identified metabolic dysregulations at the transcriptional, protein, and functional level that emerged during uncontrolled CMV infection

It is studied in research models, and its safety is not fully established

Importantly, the proteomic similarity of Day 30 iHLOs to PHHs, with a 33.46% expression difference from liver tissue, underscores their physiological relevance compared to traditional models like HepG2 cells, which exhibit a 54.36% protein difference from liver tissue, or HepaRG cells, with a 45.40% protein difference