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ANG4043, a Novel Brain-Penetrant Peptide-MAb Conjugate, Is Efficacious against HER2-Positive Intracranial Tumors in Mice

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Additionally, inhibiting SIRT1 expression inhibits SIRT1BDNFTrkB pathway activation, enhancing oxidative stress and inflammation [43]

J Clin Invest (2009) 119(11):3189202.10.1172/Jci39375 278 GunnellDOkashaMSmithGDOliverSESandhuJHollyJM

The resulting yield and fracture loci together provide a robust description of the alloys direction-dependent deformation and failure response

Immunohistochemical analysis of Iba-1 and GFAP showed that the number of activated astrocytes and microglia increased in both the striatum and substantia nigra after MPTP injection, and treatment with our formulation markedly alleviated MPTP-induced glial cell activation