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[3] Initial treatment of pernicious anemia typically consists of 1,000 mcg intramuscularly daily for one week, then weekly for four weeks, transitioning to 1,000 mcg monthly for life

Patients who are anuric or have substantially compromised kidney function should not receive glycine injections because they cannot adequately excrete the glycine load and excess fluid

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it is supported by robust, large-scale observational data from the patient community itself

Those whove tried oral supplements without experiencing symptom improvement should consider injection therapy