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Geonnotti AR, Furlow MJ, Wu T, DeSoto MG, Henderson MH, Kiser PF, et al

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63 Together, these findings indicate that (i) the sensitivity of tumors to insulin and IGF-1 parallels their response to CR, and (ii) neither the activation status of PI3KAKT per se nor mutation status of individual genes predicts for the sensitivity of tumors to both growth factors and CR

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